General Information

  • ID:  hor004829
  • Uniprot ID:  P10420
  • Protein name:  Catch-relaxing peptide
  • Gene name:  N/A
  • Organism:  Mytilus edulis (Blue mussel)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Mytilus (genus), Mytilinae (subfamily), Mytilidae (family), Mytiloidea (superfamily), Mytilida (order), Pteriomorphia, Autobranchia (subclass), Bivalvia (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0005179 hormone activity
  • GO BP:  GO:0007165 signal transduction
  • GO CC:  NA

Sequence Information

  • Sequence:  AMPMLRL
  • Length:  7(1-7)
  • Propeptide:  AMPMLRL
  • Signal peptide:  NA
  • Modification:  T7 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  This peptide exhibits both potentiating (contraction) and inhibitory (relaxation) effects on the anterior byssus retractor muscle.
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor004829_AF2.pdbhor004829_ESM.pdb

Physical Information

Mass: 93831 Formula: C36H66N10O8S2
Absent amino acids: CDEFGHIKNQSTVWY Common amino acids: LM
pI: 10.55 Basic residues: 1
Polar residues: 0 Hydrophobic residues: 3
Hydrophobicity: 101.43 Boman Index: 143
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 125.71
Instability Index: 8808.57 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  3676797
  • Title:  Catch-relaxing peptide isolated from Mytilus pedal ganglia.